Melatonin

Melatonin is an endogenously produced indoleamine also made biotechnologically for topical formulations. Serums and creams use it for antioxidant support and barrier-focused routines, with emerging but not definitive evidence for skin applications.
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Ingredient Snapshot

Overview
An antioxidant compound explored for evening skincare and barrier support.
Category
Antioxidant, Barrier Support, Soothing
Type
Antioxidant

Ingredient Ratings

Overall Rating

Good

Comedogenic Risk

None

Skin Benefits

Helps defend skin against environmental stressors and supports a stronger-feeling barrier, especially in evening routines, though evidence is promising but still maturing for topical use.

Uses In Skincare & Cosmetics

Common in night serums, face creams, and eye creams aimed at recovery-focused routines.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Usually well tolerated, though mild irritation is possible for some users; patch testing is prudent. No widely cited cosmetic regulatory restrictions at typical use levels.

Is Melatonin a Good Ingredient?

Emerging studies support antioxidant and barrier benefits in topical formats, with generally good tolerability at cosmetic concentrations, which earns it Good. The evidence is promising but not yet strong across large trials, so it hasn't reached a higher rating.

Products with Melatonin

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