Lipase is a biotechnology-derived enzyme that breaks down skin-surface triglycerides into smaller components. Oil-control cleansers and enzyme treatments use it to loosen sebum buildup and improve feel, provided the formula's pH supports its activity.
An enzyme that breaks down excess oil to help skin feel less greasy.
Category
Cleansing, Oil Control
Type
Exfoliant
Ingredient Ratings
Overall Rating
Fair
Comedogenic Risk
None
Skin Benefits
Helps break down excess surface oils to reduce greasiness and improve skin clarity when used under the right conditions, though the evidence is moderate and activity depends on pH and formula design.
Uses In Skincare & Cosmetics
Used in enzyme cleansers, oil-control face washes, and exfoliating masks or pads.
Comedogenic Rating
This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.
Safety
May cause mild irritation or stinging, especially on compromised skin or with prolonged contact; avoid the eye area and overexfoliation. Patch testing is advisable for sensitive users.
Is Lipase a Good Ingredient?
Fair fits because the sebum-breakdown benefit is real but conditional: performance is highly pH- and formula-dependent, and human data are limited. Overuse or the wrong conditions can also lead to irritation.