Hydroxypropyltrimonium Hyaluronate

Hydroxypropyltrimonium hyaluronate is a cationic, water-soluble derivative of hyaluronic acid that forms a light, flexible film on skin and hair. It boosts surface moisture retention, improves slip, and boosts a conditioned feel.
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Ingredient Snapshot

Overview
A hyaluronic acid derivative that hydrates skin and hair smoothly.
Category
Hydration, Skin Conditioning, Barrier Support
Type
Film Former

Ingredient Ratings

Overall Rating

Great

Comedogenic Risk

None

Skin Benefits

Boosts lasting hydration and leaves skin or hair feeling smoother and more manageable. Helps reduce the look of dryness-related roughness without tackiness.

Uses In Skincare & Cosmetics

Found in hydrating serums, lotions, sheet masks, conditioners, and leave-in treatments to add a silky, cushioned finish.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Considered low risk for irritation and sensitization in leave-on and rinse-off products. Rare individuals may experience mild transient redness; discontinue if discomfort occurs. No specific regulatory restrictions are commonly cited.

Is Hydroxypropyltrimonium Hyaluronate a Good Ingredient?

Rated Great because this quaternized HA shows strong substantivity and water-binding, and supplier data along with small studies point to improved moisturization and conditioning compared with standard HA. It's generally low-irritating and stays effective at modest use levels without stickiness, which sets it apart from ordinary HA derivatives.