Folate (as 5-methyltetrahydrofolate) is the bioactive form of vitamin B9 used in cosmetic formulations. It's included to provide a water-soluble vitamin component for antioxidant support and general skin-conditioning purposes.
A form of vitamin B9 that supports skin's antioxidant defenses.
Category
Antioxidant, Skin Conditioning
Type
Antioxidant
Ratings
Overall Rating
Fair
Comedogenic Risk
None
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Folate (as 5-Methyltetrahydrofolate) a Good Ingredient?
It rates Fair because the supporting evidence for topical 5-MTHF is modest and the ingredient can be unstable in water without protective formulation systems. Irritation risk is low but not zero in very sensitive skin, so this doesn't clear the bar for Good.
What it does
Skin Benefits
Supports the skin's antioxidant defenses and helps maintain a healthier-looking complexion, though topical evidence remains limited. Suitable for routines seeking a water-soluble vitamin boost.
Where you'll find it
Uses in Skincare & Cosmetics
Used in serums, gel-creams, and boosters where a vitamin B9 component is desired without oil-based carriers.
Before you use it
Safety
Generally low irritation at cosmetic levels, though degradation can occur with light and air exposure. Sensitive users should patch test before regular use.