Folate (as 5-Methyltetrahydrofolate)

Folate (as 5-methyltetrahydrofolate) is the bioactive form of vitamin B9 used in cosmetic formulations. It's included to provide a water-soluble vitamin component for antioxidant support and general skin-conditioning purposes.
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Ingredient Snapshot

Overview
A form of vitamin B9 that supports skin's antioxidant defenses.
Category
Antioxidant, Skin Conditioning
Type
Antioxidant

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Supports the skin's antioxidant defenses and helps maintain a healthier-looking complexion, though topical evidence remains limited. Suitable for routines seeking a water-soluble vitamin boost.

Uses In Skincare & Cosmetics

Used in serums, gel-creams, and boosters where a vitamin B9 component is desired without oil-based carriers.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally low irritation at cosmetic levels, though degradation can occur with light and air exposure. Sensitive users should patch test before regular use.

Is Folate (as 5-Methyltetrahydrofolate) a Good Ingredient?

It rates Fair because the supporting evidence for topical 5-MTHF is modest and the ingredient can be unstable in water without protective formulation systems. Irritation risk is low but not zero in very sensitive skin, so this doesn't clear the bar for Good.

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