Disodium Nadh

Disodium NADH is the disodium salt of reduced nicotinamide adenine dinucleotide, a water-soluble coenzyme. Cosmetics use it for antioxidant positioning and energizing themes, though evidence for meaningful topical outcomes is limited.
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Ingredient Snapshot

Overview
A coenzyme included for antioxidant appeal, with limited proof.
Category
Antioxidant
Type
Antioxidant

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Offers antioxidant support that may help diminish the look of oxidative stress, though meaningful skin benefits from topical use are not well established. Can complement energizing themes in formulas.

Uses In Skincare & Cosmetics

Included at low levels in serums, essences, and gels positioned for radiance or fatigue‑look claims; also used to bolster antioxidant blends.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Low inherent irritation potential and typically used at small amounts. Instability to light/air can reduce activity over time; discontinue if redness or discomfort occurs. No specific cosmetic regulatory restrictions are commonly cited.

Is Disodium Nadh a Good Ingredient?

Fair: topical benefits are weakly supported and the molecule is prone to oxidation, which can limit real‑world efficacy. Risk is mainly reduced performance or discoloration from instability; irritation is uncommon but possible for very sensitive skin.