Hexapeptide-9

Hexapeptide-9 is a synthetic six-amino-acid peptide used in topical skincare. It's included to improve surface smoothness and a firmer feel while softening the look of fine lines; evidence is early, so results are modest and variable.
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Ingredient Snapshot

Overview
A peptide that may smooth fine lines and add a firmer-looking feel.
Category
Anti-aging, Tone/Texture, Firming, Skin Conditioning
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Promotes a smoother, more supple appearance and refines the look of fine surface irregularities. Any firming effect is typically modest and depends on consistent use.

Uses In Skincare & Cosmetics

Used in anti-aging serums, creams, and ampoules focused on texture renewal. Also appears in sheet masks for a quick smoothing feel.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Usually well tolerated with low irritation potential; sensitive skin may see transient redness. Start slowly if layering multiple active ingredients.

Is Hexapeptide-9 a Good Ingredient?

It's Fair because the data for smoothing and firming is preliminary and the effect sizes are small, with a minor risk of irritation or sensitization for some users, which keeps expectations, and the rating, modest.

Products with Hexapeptide-9

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