Dipalmitoyl Hydroxyproline

This palmitoylated derivative of hydroxyproline is oil-soluble and used as a skin-conditioning emollient in cosmetics. It's chosen to add slip, cushion, and a firmer feel in leave-on creams, serums, and eye formulas.
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Ingredient Snapshot

Overview
An emollient that smooths skin and may support a firmer look.
Category
Firming, Skin Conditioning
Type
Emollient

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Helps skin feel smoother and more supple with a soft, conditioned finish. May promote a firmer-looking complexion, though supporting evidence is limited.

Uses In Skincare & Cosmetics

Found in anti-aging serums, moisturizers, and eye creams to deliver a velvety application and refined afterfeel.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally regarded as low-irritation, but patch test if you’re sensitive or acne-prone due to its fatty character. No widely cited regulatory restrictions. Discontinue if redness or bumps develop.

Is Dipalmitoyl Hydroxyproline a Good Ingredient?

Fair: it mainly acts as an emollient that improves feel, while evidence for firming or anti-wrinkle effects in real-world use is limited. Those with very oily or clog-prone skin may experience breakouts, and mild irritation is possible around delicate areas.

Products with Dipalmitoyl Hydroxyproline

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