Tetrapeptide-4

Tetrapeptide-4 is a man-made peptide of four amino acids designed for easy inclusion in water-soluble skincare. It's used for skin conditioning and a smoother, more even look in primers and serums, though current independent evidence is limited.
Like this ingredient?

Ingredient Snapshot

Overview
A peptide used to smooth texture and even out skin's appearance.
Category
Skin Conditioning, Anti-aging, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May reduce the look of rough texture and promote a more uniform complexion. Research to date is preliminary.

Uses In Skincare & Cosmetics

Found in brightening serums, makeup primers, and hydrating gels to create a smoother canvas.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally low irritation potential and unlikely to clog pores, but discontinue if redness or stinging develops. No known special cosmetic regulatory restrictions.

Is Tetrapeptide-4 a Good Ingredient?

It rates Fair since evidence for improving tone and texture is still early-stage, keeping expectations modest. There's also a slight risk of irritation or sensitization, particularly near the eyes.

Products with Tetrapeptide-4

Related Ingredients