Snapshot
- Overview
- A synthetic peptide meant to refine skin's smoothness and tone.
- Category
- Anti-aging, Skin Conditioning, Tone/Texture
- Type
- Peptide
Tetrapeptide-21
Tetrapeptide-21 is a synthetic peptide made of four amino acids designed for cosmetic use. Formulators use it to improve the look of skin smoothness and tone; current support comes mainly from limited manufacturer studies.
Like this ingredient?
Our take
Is Tetrapeptide-21 a Good Ingredient?
It rates Fair due to limited independent clinical evidence, since most performance claims come from small supplier studies. A minority of users may experience mild irritation or sensitization, and results depend heavily on the formula.
What it does
Skin Benefits
Helps refine skin texture and supports a smoother-looking complexion; backing is limited and mainly from supplier testing.
Where you'll find it
Uses in Skincare & Cosmetics
Used in anti-aging serums, lotions, and eye creams targeting fine lines and an uneven look.
Before you use it
Safety
Typically well tolerated, though peptides can occasionally cause transient redness or tingling, especially near the eyes or on compromised skin. No widely recognized regulatory limits at standard cosmetic concentrations.
Products with Tetrapeptide-21
