Tetrapeptide-14

Tetrapeptide-14 is a synthetic four-residue peptide optimized for water-based, leave-on skincare. It's selected for comfort-focused, sensitive-skin routines and general conditioning in light serums or gels, but strong independent support is still limited.
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Ingredient Snapshot

Overview
A peptide formulated to comfort sensitive, reactive-feeling skin.
Category
Soothing, Sensitive Skin, Skin Conditioning
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Targets visible redness and signs of discomfort in reactive skin. Independent evidence remains limited.

Uses In Skincare & Cosmetics

Common in calming serums, lightweight moisturizers, and post-procedure sheet masks for easily irritated skin.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Usually well tolerated and suitable for sensitive-skin products, but patch testing is advisable if you're reactive. No commonly recognized cosmetic regulatory restrictions.

Is Tetrapeptide-14 a Good Ingredient?

It's Fair because soothing and anti-redness claims lack solid independent clinical backing, even though the peptide is formulated to be gentle. Even calming peptides like this one can occasionally trigger sensitivity.