Tetrapeptide-1

Tetrapeptide-1 is a lab-designed chain of four amino acids formulated for water-based skincare. It's included to condition skin in anti-aging routines and as a gentle add-on in serums and creams, though solid, independent efficacy data remain limited.
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Ingredient Snapshot

Overview
A lab-made peptide added to anti-aging formulas to help condition skin.
Category
Anti-aging, Skin Conditioning, Soothing
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May soften the look of fine lines and support a smoother, more resilient complexion. Evidence independent of supplier data is modest.

Uses In Skincare & Cosmetics

Used in essences, eye gels, and lightweight serums to complement actives or round out hydrating routines.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally well tolerated in leave-on formulas with low irritation likelihood. Patch test if you have sensitive skin. No widely recognized cosmetic regulatory restrictions.

Is Tetrapeptide-1 a Good Ingredient?

It rates Fair because the line-softening benefits rely largely on preliminary or supplier studies rather than independent research, so expectations should stay modest. Minor sensitization or stinging can occur in some users, adding a small tolerability caveat.