Sh-Polypeptide-9

Sh-Polypeptide-9 is a lab-synthesized, water-soluble polypeptide patterned after human protein domains. Formulators use it to condition skin and support a firmer, more even look, but evidence remains limited and user experience is inconsistent.
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Ingredient Snapshot

Overview
A synthetic peptide that may help skin look firmer and smoother.
Category
Anti-aging, Firming, Skin Conditioning, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

It may help skin look firmer and more refined, with some smoothing potential, though the supporting data are sparse and results vary from person to person.

Uses In Skincare & Cosmetics

It shows up mostly in concentrated serums and eye gels aimed at a tauter look, and occasionally in leave-on masks or moisturizers.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

It's generally well tolerated in serums and creams, though occasional transient stinging can happen. Patch testing is a good idea for delicate or compromised skin. No specific regulatory limits are commonly cited for it.

Is Sh-Polypeptide-9 a Good Ingredient?

The Fair rating comes down to thin research: there isn't much data behind this peptide, and outcomes are inconsistent enough that expectations should stay modest. It also carries a small risk of irritation or sensitization for sensitive users, which keeps it from scoring higher.

Products with Sh-Polypeptide-9

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