Sh-Polypeptide-50

Sh-Polypeptide-50 is a laboratory-produced, water-soluble peptide made through biotechnology. It's added to condition skin and improve surface feel; data are preliminary, and performance varies with use level.
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Ingredient Snapshot

Overview
A lab-made peptide that conditions skin for a smoother surface.
Category
Skin Conditioning, Anti-aging, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Used consistently, it aims to improve softness and give skin a velvety finish. The evidence for this is still preliminary, so any change is likely to be incremental.

Uses In Skincare & Cosmetics

It's used in moisturizers, leave-on masks, and makeup-priming lotions to smooth the skin before application.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

There are no known ingredient-specific regulatory restrictions, and standard cosmetic use is considered low risk. Minor irritation can happen, particularly on compromised skin, so avoid applying it to broken or freshly exfoliated areas.

Is Sh-Polypeptide-50 a Good Ingredient?

The Fair rating reflects how preliminary the data still is: real-world efficacy is uncertain, and whatever benefit shows up is likely to be subtle and formula-dependent rather than reliable. Some users also report mild stinging or redness.