Sh-Polypeptide-3

Sh-Polypeptide-3 is a biotechnology-derived, water-soluble cosmetic peptide. It's used to condition skin and smooth the look of tone and texture; evidence is limited, so results depend on concentration and overall formula.
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Ingredient Snapshot

Overview
A peptide that conditions skin and helps smooth tone and texture.
Category
Skin Conditioning, Anti-aging, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Good

Comedogenic Risk

None

Skin Benefits

It helps skin feel softer and look more polished, for a fresher overall appearance. The effects tend to be subtle, since the evidence behind it is still limited.

Uses In Skincare & Cosmetics

You'll find it in serums, essences, and lightweight gels meant for daily smoothing, as well as in moisturizers where it layers easily.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

It's typically low risk in leave-on products and isn't known to cause photosensitivity or clog pores. Sensitive skin may still see mild irritation or an allergic reaction, so a patch test is worthwhile. There are no well-established regulatory restrictions on this class of ingredient.

Is Sh-Polypeptide-3 a Good Ingredient?

This growth factor peptide earns a Good rating: it plausibly supports the skin's natural repair processes and helps texture look smoother, and it's a common ingredient in higher-end lines targeting fine lines and general rejuvenation. It falls short of Great because the evidence for those repair claims is still thin relative to better-studied peptides.

Products with Sh-Polypeptide-3

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