Sh-Polypeptide-3

Sh-Polypeptide-3 is a biotechnology-derived, water-soluble cosmetic peptide. It's used to condition skin and smooth the look of tone and texture; evidence is limited, so results depend on concentration and overall formula.
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Snapshot

Overview
A peptide that conditions skin and helps smooth tone and texture.
Category
Skin Conditioning, Anti-aging, Tone/Texture
Type
Peptide

Ratings

Overall Rating

Good

Comedogenic Risk

None

Not typically evaluated for comedogenicity — no standardized rating available.

Is Sh-Polypeptide-3 a Good Ingredient?

This growth factor peptide earns a Good rating: it plausibly supports the skin's natural repair processes and helps texture look smoother, and it's a common ingredient in higher-end lines targeting fine lines and general rejuvenation. It falls short of Great because the evidence for those repair claims is still thin relative to better-studied peptides.

Skin Benefits

It helps skin feel softer and look more polished, for a fresher overall appearance. The effects tend to be subtle, since the evidence behind it is still limited.

Uses in Skincare & Cosmetics

You'll find it in serums, essences, and lightweight gels meant for daily smoothing, as well as in moisturizers where it layers easily.

Safety

It's typically low risk in leave-on products and isn't known to cause photosensitivity or clog pores. Sensitive skin may still see mild irritation or an allergic reaction, so a patch test is worthwhile. There are no well-established regulatory restrictions on this class of ingredient.