Sh-Polypeptide-22

Sh-Polypeptide-22 is a bioengineered, water-soluble cosmetic polypeptide made via recombinant methods. It's used for skin conditioning and to smooth visible texture; support is modest and outcomes depend on dose and formulation.
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Ingredient Snapshot

Overview
A bioengineered peptide that conditions skin and softens texture.
Category
Skin Conditioning, Anti-aging, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

With routine use it may soften the look of fine lines and add suppleness, though any improvement tends to be modest and depends heavily on the rest of the formula.

Uses In Skincare & Cosmetics

It appears in anti-aging serums and eye creams, and sometimes in concentrated ampoules for nighttime routines.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

It's water-soluble and generally well tolerated, with a low chance of clogging pores or causing photosensitivity. Patch test if your skin tends to react, and stop use if redness or itching shows up.

Is Sh-Polypeptide-22 a Good Ingredient?

It lands at Fair because the evidence for visible smoothing from this recombinant peptide is modest and depends heavily on formulation and dose, so results aren't consistent enough to rate higher. Peptide actives like this one also carry a small risk of irritation or sensitization.

Products with Sh-Polypeptide-22

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