rh-Polypeptide-1

rh-Polypeptide-1 is a recombinant human polypeptide made by controlled fermentation and purification for cosmetic use. It's used to improve the look of surface smoothness and resilience, though supporting research is modest and improvements are usually subtle.
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Ingredient Snapshot

Overview
A lab-made peptide that aims for smoother, more resilient skin.
Category
Skin Conditioning, Tone/Texture, Firming
Type
Peptide

Ingredient Ratings

Overall Rating

Good

Comedogenic Risk

None

Skin Benefits

Can give skin a more polished appearance and a springier feel, though evidence outside supplier data is limited, so consistency of results varies.

Uses In Skincare & Cosmetics

Formulated into serums and creams, and sometimes ampoules, often alongside humectants or antioxidants in daily routines.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

No specific concerns at customary cosmetic concentrations. Patch test if you have reactive or compromised skin and avoid continued use if irritation develops.

Is rh-Polypeptide-1 a Good Ingredient?

Good, because as a bioengineered growth factor it plausibly supports skin regeneration and softens the look of fine lines and wrinkles, and it's widely regarded as a high-value ingredient in advanced anti-aging products. Independent evidence beyond supplier research is still limited, which is why it sits at Good rather than Great.

Products with rh-Polypeptide-1

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