Pentapeptide-59

Pentapeptide-59 is a laboratory-made, water-soluble peptide made of five amino acids. Skin-conditioning products use it to improve product feel and evenness of application, though publicly available performance data are still preliminary.
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Ingredient Snapshot

Overview
A peptide meant to make skin feel softer and more evenly textured.
Category
Skin Conditioning
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Contributes to a softer, more even-feeling skin surface; current performance data are preliminary and outcomes can vary.

Uses In Skincare & Cosmetics

Found in daily creams, gel hydrators, and toning essences to elevate application feel and skin touch.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Considered low likelihood for irritation, but transient redness or tingling may occur at higher use levels or on reactive skin. Discontinue if persistent sensitivity develops.

Is Pentapeptide-59 a Good Ingredient?

Rated Fair because the public performance data are preliminary, so effects on skin feel may be subtle and variable. It's generally low-risk, but some users can experience mild irritation or sensitization, which keeps it out of Good territory.