Pentapeptide-4

Pentapeptide-4 is a short, water-soluble peptide made of five amino acids used in cosmetic formulations. It's included to support goals like smoother texture and a more refined look, though evidence for specific performance is limited.
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Ingredient Snapshot

Overview
A peptide meant to make skin's surface look smoother and more even.
Category
Tone/Texture, Skin Conditioning
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May promote a more even-looking skin surface and a softer appearance of roughness; available data is limited, so outcomes can vary. Offers a lightweight way to complement texture-smoothing routines.

Uses In Skincare & Cosmetics

Included in serums, essences, and daily moisturizers designed for texture refinement in non-invasive skincare regimens.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally considered low risk at cosmetic use levels, but mild irritation or sensitization can occur, particularly on sensitive skin. Patch testing is advisable for first-time users. No widely noted regulatory restrictions for typical skincare use.

Is Pentapeptide-4 a Good Ingredient?

Rated Fair because the clinical support for visible texture improvement is limited, so results can be modest or variable. There's also a small risk of irritation or sensitization for some users, especially in leave-on formulas, which keeps it below Good.

Products with Pentapeptide-4

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