Palmitoyl Tripeptide-38

Palmitoyl tripeptide-38 is a modified signaling peptide with a palmitic anchor that improves its affinity for skin. Leave-on care includes it to promote smoother-looking texture and a sense of increased firmness with regular use.
Like this ingredient?

Ingredient Snapshot

Overview
A peptide that helps blur fine lines and gives skin a firmer look.
Category
Anti-aging, Firming, Tone/Texture, Skin Conditioning
Type
Peptide

Ingredient Ratings

Overall Rating

Good

Comedogenic Risk

None

Skin Benefits

Visibly blurs fine lines and supports a more lifted, refined appearance with consistent use. Improves surface smoothness for a polished look.

Uses In Skincare & Cosmetics

Frequently found in eye creams, wrinkle serums, and plumping night creams. Also used in rich moisturizers targeting line-smoothing care.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Considered well tolerated for most users, with occasional mild irritation possible in sensitive skin. Patch testing is advisable; no specific regulatory limits commonly noted.

Is Palmitoyl Tripeptide-38 a Good Ingredient?

Rated Good because small in-vivo studies, often supplier-run, suggest visible wrinkle-smoothing, and its palmitoylated form improves stability and skin compatibility with a low irritation profile. It doesn't go higher because the supporting studies are mostly small and industry-sponsored rather than independent.

Products with Palmitoyl Tripeptide-38

Related Ingredients