Palmitoyl Tripeptide-1

Palmitoyl tripeptide-1 is a palmitic-acid-linked signaling peptide used in cosmetic formulations. Leave-on products include it to improve the look of smooth texture and a firmer feel with continued use.
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Ingredient Snapshot

Overview
A signaling peptide that helps soften fine lines and firm skin's look.
Category
Anti-aging, Firming, Skin Conditioning, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Good

Comedogenic Risk

None

Skin Benefits

Helps soften the appearance of fine lines and promotes a bouncier, more supple look over time. Supports a smoother-looking complexion with regular use.

Uses In Skincare & Cosmetics

Often included in eye treatments, moisturizing lotions, and leave-on serums. Also found in richer night creams targeting visible lines.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally well tolerated in leave-on products; irritation is uncommon but possible for very sensitive skin. Patch test if you're reactive; no specific regulatory limits commonly noted.

Is Palmitoyl Tripeptide-1 a Good Ingredient?

Rated Good on the strength of small human studies and long-standing cosmetic use showing modest line-smoothing; the palmitoyl group also improves stability and skin affinity, with typically low irritation. Its modest, incremental evidence base is what keeps it from a higher rating.

Products with Palmitoyl Tripeptide-1

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