Palmitoyl Tetrapeptide-95

Palmitoyl Tetrapeptide-95 is a lab-made four-amino-acid peptide coupled to a fatty chain for topical use. It appears in skincare aimed at conditioning and a more even-looking tone, though the supporting literature is modest and still developing.
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Ingredient Snapshot

Overview
A peptide aimed at smoother skin and a more even-looking tone.
Category
Skin Conditioning, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May help promote a smoother-looking complexion and more even visual tone; current backing is modest and still developing. Expectations should remain conservative pending more research.

Uses In Skincare & Cosmetics

Included in multi-peptide serums, primers, and night creams to round out broader skincare regimens.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Likely low overall irritation, yet caution is prudent given the limited evidence; patch test before regular use. Discontinue if persistent discomfort occurs. No known specific regulatory limitations for routine cosmetic use.

Is Palmitoyl Tetrapeptide-95 a Good Ingredient?

Rated Fair because current support is mostly preliminary or supplier-based, so visible improvements may be limited. Sensitive individuals may also experience mild irritation, which keeps it from a Good rating.