A palmitoylated dipeptide combining diaminobutyroyl and hydroxythreonine, made for topical formulas. It's used to improve the look of skin firmness and texture, though independent efficacy data are limited and largely come from suppliers.
A peptide meant to make skin look firmer and more refined.
Category
Firming, Tone/Texture, Skin Conditioning
Type
Peptide
Ratings
Overall Rating
Fair
Comedogenic Risk
None
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine a Good Ingredient?
Rated Fair because the efficacy evidence is mostly supplier-led with limited independent clinical data, so benefits may be modest. Mild irritation or sensitization can also occur in sensitive areas like the eye contour, which together keep it below Good.
What it does
Skin Benefits
May help skin feel bouncier and look more refined; most data come from supplier studies, so results can vary.
Where you'll find it
Uses in Skincare & Cosmetics
Often included in serums or eye creams targeting firmness, and added to moisturizers as a peptide booster.
Before you use it
Safety
Generally low risk at typical cosmetic levels, but peptides can cause transient redness or stinging in reactive skin; patch test recommended. No specific regulatory restrictions are commonly cited for this ingredient.
Products with Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine