Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine

A palmitoylated dipeptide combining diaminobutyroyl and hydroxythreonine, made for topical formulas. It's used to improve the look of skin firmness and texture, though independent efficacy data are limited and largely come from suppliers.
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Ingredient Snapshot

Overview
A peptide meant to make skin look firmer and more refined.
Category
Firming, Tone/Texture, Skin Conditioning
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May help skin feel bouncier and look more refined; most data come from supplier studies, so results can vary.

Uses In Skincare & Cosmetics

Often included in serums or eye creams targeting firmness, and added to moisturizers as a peptide booster.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally low risk at typical cosmetic levels, but peptides can cause transient redness or stinging in reactive skin; patch test recommended. No specific regulatory restrictions are commonly cited for this ingredient.

Is Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine a Good Ingredient?

Rated Fair because the efficacy evidence is mostly supplier-led with limited independent clinical data, so benefits may be modest. Mild irritation or sensitization can also occur in sensitive areas like the eye contour, which together keep it below Good.

Products with Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine

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