Oligopeptide-29

Oligopeptide-29 is a lab-synthesized short-chain peptide used in topical cosmetic products, added to serums and creams to condition skin feel and improve surface smoothness, though independent evidence for distinct effects remains limited.
Like this ingredient?

Ingredient Snapshot

Overview
A peptide meant to smooth skin's surface, though evidence is thin.
Category
Skin Conditioning, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May support a smoother-feeling surface and a softer appearance; current research is sparse. Visible changes, if any, are typically modest and formula-dependent.

Uses In Skincare & Cosmetics

Used in serums, essences, and moisturizers to boost slip and elegant application. Also appears in leave-on treatments aimed at refined skin feel.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally considered low risk in topical use. Patch test if reactive or when layering multiple actives. No specific regulatory restrictions are widely cited for this peptide.

Is Oligopeptide-29 a Good Ingredient?

Rated Fair due to limited peer-reviewed data on any unique skin benefit, with performance depending heavily on the vehicle it's formulated in. Irritation is generally low, but sensitivities can occur in complex formulas, which is enough to keep it out of Good territory.