Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2

This is a laboratory-engineered peptide duo inspired by Nicotiana benthamiana, combining octapeptide-30 and sh-oligopeptide-2, used in modern serums to improve the look of skin smoothness and bounce, though evidence remains limited.
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Ingredient Snapshot

Overview
A lab-engineered peptide duo meant to smooth and lift skin's look.
Category
Anti-aging, Skin Conditioning, Firming, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May help skin look more lifted and refined, supporting the appearance of smoother texture, though evidence is early-stage, so results can be subtle and vary by formula.

Uses In Skincare & Cosmetics

Common in lightweight serums, ampoules, and eye gels aimed at fine lines and slackness.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally considered low to moderate irritation potential, but patch testing is sensible for reactive skin. No widely recognized regulatory restrictions for topical use. Discontinue if redness or stinging develops.

Is Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 a Good Ingredient?

The data behind this are early and mostly supplier-led, with uncertain real-world impact and typical peptide delivery and stability limitations, so results may be modest, which is why it rates Fair. A small risk of mild irritation or sensitization exists, especially in complex active formulas.

Products with Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2

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