This is a laboratory-engineered peptide duo inspired by Nicotiana benthamiana, combining octapeptide-30 and sh-oligopeptide-2, used in modern serums to improve the look of skin smoothness and bounce, though evidence remains limited.
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 a Good Ingredient?
The data behind this are early and mostly supplier-led, with uncertain real-world impact and typical peptide delivery and stability limitations, so results may be modest, which is why it rates Fair. A small risk of mild irritation or sensitization exists, especially in complex active formulas.
What it does
Skin Benefits
May help skin look more lifted and refined, supporting the appearance of smoother texture, though evidence is early-stage, so results can be subtle and vary by formula.
Where you'll find it
Uses in Skincare & Cosmetics
Common in lightweight serums, ampoules, and eye gels aimed at fine lines and slackness.
Before you use it
Safety
Generally considered low to moderate irritation potential, but patch testing is sensible for reactive skin. No widely recognized regulatory restrictions for topical use. Discontinue if redness or stinging develops.
Products with Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2