Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76

Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76 is a plant-expressed peptide fragment generated through biotechnology. Formulators use it for firmer tone and improved skin look, though current human clinical support for topical use is sparse.
Like this ingredient?

Ingredient Snapshot

Overview
A plant-based peptide meant to give skin a firmer, more even tone.
Category
Anti-aging, Tone/Texture, Firming, Skin Conditioning
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Can lend a subtly more elastic, smoother appearance, though published human data are sparse and effects may be modest; works best alongside proven actives.

Uses In Skincare & Cosmetics

Frequently incorporated into firming creams, ampoules, and eye gels, and sometimes added to serums aimed at tone and texture refinement.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Typically low risk of irritation, though peptide fragments may cause sensitivity in susceptible individuals. Patch test before regular use and avoid broken or inflamed skin.

Is Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76 a Good Ingredient?

It's included for firming and texture support, yet topical human data remain limited, which is why it rates Fair; results are uncertain and typically subtle without complementary actives.

Products with Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76

Related Ingredients