Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1

Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1 is a biotechnology-derived signaling peptide produced via plant expression systems, used to promote smoother, firmer-looking skin, though peer-reviewed clinical data for topicals are limited.
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Ingredient Snapshot

Overview
A lab-made peptide aimed at smoother, firmer-looking skin.
Category
Anti-aging, Tone/Texture, Firming, Skin Conditioning
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May refine surface texture and lend a temporarily plumped appearance, though current human evidence remains limited, so outcomes vary; best seen as a supporting anti-aging component.

Uses In Skincare & Cosmetics

Formulated into targeted serums, eye creams, and sheet masks within anti-aging routines, and occasionally into lightweight moisturizers.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally low irritation potential, though peptides can still trigger sensitivity in some users. Patch test first and discontinue if irritation develops.

Is Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 a Good Ingredient?

This is promising peptide technology, yet human clinical support for topical efficacy is limited, which is why it rates Fair; the benefits are likely modest and formula-dependent, with some sensitivity possible.

Products with Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1

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