Myristoyl Tetrapeptide-13

Myristoyl tetrapeptide-13 is a four-amino-acid peptide conjugated with myristic acid for improved topical delivery, used in lotions and eye products for a supple, resilient appearance, though support from peer-reviewed studies is modest.
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Ingredient Snapshot

Overview
A peptide used in eye creams to make skin look elastic and cushioned.
Category
Anti-aging, Firming, Tone/Texture, Skin Conditioning
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May help skin appear more elastic and cushioned, particularly in delicate areas, though research to date is modest; can contribute to a smoother-looking eye area without medical claims.

Uses In Skincare & Cosmetics

Used in eye creams, silky lotions, and facial serums; also appears in rich night moisturizers for supportive care.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Usually well tolerated with low to moderate irritation potential depending on concentration and formulation. No routine regulatory restrictions are noted for typical cosmetic use; patch test if you have reactive skin.

Is Myristoyl Tetrapeptide-13 a Good Ingredient?

It can improve a supple, resilient appearance, but backing from peer-reviewed studies is modest, so the effects may be subtle, which is why it rates Fair. Mild sensitivity is a possible risk with peptide actives.