Myristoyl Hexapeptide-23

Myristoyl hexapeptide-23 is a palmitoyl-like, myristoylated six-amino-acid peptide designed for topical delivery in cosmetic formulas, used in serums and creams for a smoother, firmer-looking complexion, though published evidence remains limited.
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Ingredient Snapshot

Overview
A peptide that may help skin look firmer and feel bouncier over time.
Category
Anti-aging, Firming, Tone/Texture, Skin Conditioning
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May help skin look more taut and feel bouncier with continued use, though available evidence is preliminary; offers a subtly smoother look without acting as a drug.

Uses In Skincare & Cosmetics

Often included in lightweight serums, ampoules, and night creams; also used in eye gels targeting a refreshed look.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Typically well tolerated with a low irritation profile, though mild stinging or redness can occur in sensitive skin. No known specific regulatory restrictions at customary cosmetic concentrations; patch test if reactive.

Is Myristoyl Hexapeptide-23 a Good Ingredient?

It offers a cosmetic smoothing and firming look, but published, peer-reviewed evidence is limited, so results may be modest and variable, which is why it rates Fair. Minor sensitivity is possible from the peptide or its lipid carrier systems.