Myristoyl hexapeptide-23 is a palmitoyl-like, myristoylated six-amino-acid peptide designed for topical delivery in cosmetic formulas, used in serums and creams for a smoother, firmer-looking complexion, though published evidence remains limited.
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Myristoyl Hexapeptide-23 a Good Ingredient?
It offers a cosmetic smoothing and firming look, but published, peer-reviewed evidence is limited, so results may be modest and variable, which is why it rates Fair. Minor sensitivity is possible from the peptide or its lipid carrier systems.
What it does
Skin Benefits
May help skin look more taut and feel bouncier with continued use, though available evidence is preliminary; offers a subtly smoother look without acting as a drug.
Where you'll find it
Uses in Skincare & Cosmetics
Often included in lightweight serums, ampoules, and night creams; also used in eye gels targeting a refreshed look.
Before you use it
Safety
Typically well tolerated with a low irritation profile, though mild stinging or redness can occur in sensitive skin. No known specific regulatory restrictions at customary cosmetic concentrations; patch test if reactive.