Heptasodium Hexacarboxymethyl Dipeptide-12

Heptasodium hexacarboxymethyl dipeptide-12 is a water-soluble, peptide-based chelating agent used in personal care products. It's added to bind metal ions, support preservative systems, and improve formula stability and clarity across varied pH conditions.
Like this ingredient?

Ingredient Snapshot

Overview
A peptide-based ingredient that binds metals to keep formulas stable.
Category
Preservative
Type
Chelating Agent

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Reduces metal-catalyzed degradation for more consistent appearance and performance. Can support preservative effectiveness without altering sensory feel.

Uses In Skincare & Cosmetics

Used in water-based shampoos, gels, toners, cleansers, and serums to help formulas remain clear and stable across a wide pH range.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally low risk at typical use levels, though slight irritation can occur in reactive skin. No commonly cited major regulatory restrictions.

Is Heptasodium Hexacarboxymethyl Dipeptide-12 a Good Ingredient?

It's Fair because its benefits are indirect and formulation-focused, with limited evidence for direct skin effects, and mild irritation is possible in very sensitive users. It's a useful stabilizer rather than an active, which is why the rating stays moderate.