Glycylglycine

A simple dipeptide composed of two glycine units, readily soluble in water and compatible with aqueous systems. It's used to adjust pH and support stability, with limited evidence for direct skin-conditioning.
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Ingredient Snapshot

Overview
A simple dipeptide that helps balance formulas and smooth skin's feel.
Category
Skin Conditioning
Type
Buffer

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

May help skin feel smoother and more comfortable by supporting a balanced environment; evidence for direct skin benefits is limited. Contributes to a more consistent feel in products used daily.

Uses In Skincare & Cosmetics

Commonly used in water-based serums, toners, and essences as a pH-buffering component. Also appears in gel creams to help maintain formula performance over time.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Typically low risk at cosmetic use levels, though mild, transient irritation can occur. No widely recognized topical regulatory restrictions.

Is Glycylglycine a Good Ingredient?

It's Fair because it functions mainly as a pH-buffering dipeptide, and evidence for direct skin benefits beyond that is limited. At higher levels it can shift product pH and may cause minor stinging in sensitive skin, which is what keeps the rating in the middle.

Products with Glycylglycine

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