Dimethyl sulfone (MSM) is an organic sulfur compound classified as a water-soluble humectant. Skincare uses it to support surface hydration and a smoother feel; broader cosmetic benefits are still under study and evidence for topical use is limited.
MSM, a sulfur compound that helps skin hold onto moisture.
Category
Soothing, Hydration, Sensitive Skin
Type
Humectant
Ratings
Overall Rating
Fair
Comedogenic Risk
None
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Dimethyl Sulfone a Good Ingredient?
Rated Fair: it offers modest humectant support for softness, but strong clinical data for broader topical skin benefits are limited, and some users may notice mild stinging.
What it does
Skin Benefits
Helps skin retain water for a softer, cushioned feel. Broader cosmetic benefits are not well established for topical use.
Where you'll find it
Uses in Skincare & Cosmetics
Included in moisturizers, soothing lotions, and wash-off masks aimed at comfort and hydration, including options for sensitive-prone skin.
Before you use it
Safety
Generally low irritation risk, though slight stinging or redness can occur on sensitive skin. Discontinue if persistent irritation develops.