D-Arginyl Tyrosinyl Ornithinyl Phenylalanine

This biotechnology-derived oligopeptide is composed of arginine, tyrosine, ornithine, and phenylalanine. It's used to improve the look of tone and texture and for conditioning effects, though available evidence is limited.
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Ingredient Snapshot

Overview
A lab-made peptide meant to even tone and smooth texture.
Category
Skin Conditioning, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Supports a more uniform-looking tone and a smoother surface appearance, though evidence remains limited. Can help skin feel conditioned and refined.

Uses In Skincare & Cosmetics

Found in targeted serums, eye creams, and daily moisturizers that focus on radiance and texture refinement.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally low irritation potential, but sensitive skin can react to new peptides or accompanying formulary components; patch test if prone to redness. No well-known regulatory restrictions for this peptide in cosmetics.

Is D-Arginyl Tyrosinyl Ornithinyl Phenylalanine a Good Ingredient?

Rated Fair because evidence for tone and texture benefits is preliminary and not widely replicated in independent studies. While peptides are generally low risk, some individuals may experience mild irritation or no visible improvement.

Products with D-Arginyl Tyrosinyl Ornithinyl Phenylalanine

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