Cetylhydroxyproline Palmitamide

Cetylhydroxyproline Palmitamide is a pseudo-ceramide lipid amide from hydroxyproline and palmitic acid used as an emollient. It's used to mimic skin lipids, curb moisture loss, increase suppleness, and leave a smooth, conditioned finish.
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Ingredient Snapshot

Overview
A ceramide-like lipid that reinforces the skin barrier and eases dryness.
Category
Barrier Support, Skin Conditioning, Hydration
Type
Emollient

Ingredient Ratings

Overall Rating

Good

Comedogenic Risk

None

Skin Benefits

Helps reinforce the skin’s protective layer, easing feelings of dryness and tightness. Leaves skin feeling supple and more comfortable.

Uses In Skincare & Cosmetics

Common in rich creams, balms, and overnight masks to cushion the skin; also appears in eye creams targeting delicate areas.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally well tolerated; fatty amide structures are unlikely to irritate, though rare individuals may experience sensitivity. Appropriate for daily leave‑on use unless irritation occurs.

Is Cetylhydroxyproline Palmitamide a Good Ingredient?

This pseudo‑ceramide emollient helps support barrier lipids and reduce moisture loss, with some supportive data and a low tendency to irritate. That combination of solid performance and generally low risk earns it a Good rating, short of Great.

Products with Cetylhydroxyproline Palmitamide

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