Ceramide 6-II

Ceramide 6-II is a skin-mimicking lipid (ceramide AP) associated with the epidermis's protective lipid matrix. It's included in creams and cleansers to strengthen barrier support, improve moisture retention, and boost flexibility and overall skin feel.
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Ingredient Snapshot

Overview
A ceramide that reduces flakiness and boosts skin's flexibility.
Category
Barrier Support, Hydration, Sensitive Skin, Skin Conditioning
Type
Emollient

Ingredient Ratings

Overall Rating

Great

Comedogenic Risk

None

Skin Benefits

Helps reduce visible flakiness and improves the feeling of suppleness and bounce, and skin tends to feel more comfortable and even-textured through the day.

Uses In Skincare & Cosmetics

Common in milky toners, essences, and body creams for everyday maintenance, and also found in hand creams and leave-on treatments to support ongoing comfort.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Typically non-sensitizing and well tolerated, even for dryness-prone or sensitive skin. Irritation is uncommon and more likely from other components in the product.

Is Ceramide 6-II a Good Ingredient?

Ceramide AP is skin-mimicking, with published support, often in multi-ceramide systems, for barrier reinforcement and reduced transepidermal water loss, and it shows good formulation stability, which earns it a Great rating; it's generally low-irritating and suitable for ongoing use.