Arginine/Lysine Polypeptide

This lab-created polypeptide is built from arginine and lysine amino acid residues. Leave-on skincare uses it to support a firmer, smoother feel and boost surface texture, though peer-reviewed evidence is moderate and outcomes vary with formula and routine.
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Ingredient Snapshot

Overview
A peptide that supports firmer, smoother-looking skin over time.
Category
Anti-aging, Firming, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Supports a springier feel and a more refined surface appearance. Visible effects are often subtle and require consistent use.

Uses In Skincare & Cosmetics

Common in firming serums, eye creams, and leave-on treatments, and sometimes incorporated into sheet masks for a quick boost.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally low risk, though peptides can occasionally trigger mild irritation or redness; patch testing is prudent for sensitive skin. Avoid getting product into the eyes and discontinue if irritation persists.

Is Arginine/Lysine Polypeptide a Good Ingredient?

That puts it at Fair: proposed to promote a firmer, smoother look, but clinical backing is limited and effects can be subtle. Mild irritation or sensitization may occur, particularly near the eye area.

Products with Arginine/Lysine Polypeptide

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