Acetylarginyltryptophyl diphenylglycine is a lab-made tripeptide derivative of arginine, tryptophan, and diphenylglycine built for cosmetics. It works as a gentle conditioning peptide, supporting comfort and a smoother feel in sensitive-skin formulas.
A gentle peptide that helps sensitive skin feel calm and smooth.
Category
Skin Conditioning, Sensitive Skin
Type
Peptide
Ratings
Overall Rating
Fair
Comedogenic Risk
None
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Acetylarginyltryptophyl Diphenylglycine a Good Ingredient?
This one rates Fair due to limited independent clinical evidence for skin benefits, with most support coming from supplier data. Mild irritation is possible in very sensitive skin or when layered with strong actives.
What it does
Skin Benefits
May help skin feel calmer and more comfortable while supporting a smoother feel; evidence is preliminary and results can vary. Suitable for routines seeking gentle support without strong actives.
Where you'll find it
Uses in Skincare & Cosmetics
Often included in lightweight moisturizers, soothing serums, and post-cleanse mists designed for delicate skin.
Before you use it
Safety
Usually low risk, but may cause transient stinging or redness in reactive skin; patch testing is advisable. If you experience sensitivity, avoid combining with potent exfoliants or retinoids.
Products with Acetylarginyltryptophyl Diphenylglycine