Acetyl Glutamine

Acetyl Glutamine is an acetylated form of the amino acid glutamine, used in cosmetics as a water-binding humectant. It attracts moisture and promotes a supple feel, complementing barrier-care formulas, though evidence for it is limited.
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Ingredient Snapshot

Overview
A moisture-binding amino acid that leaves skin feeling quenched.
Category
Hydration, Barrier Support, Skin Conditioning
Type
Humectant

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Helps skin feel quenched and comfortable, lending a fresher, cushioned look. Evidence is preliminary, so outcomes may be modest.

Uses In Skincare & Cosmetics

Common in hydrating serums, toners, and gel moisturizers designed for daily moisture support and resilience against dryness.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally considered low risk in leave-on products, but patch testing is advisable for reactive skin. No specific regulatory limits are commonly cited.

Is Acetyl Glutamine a Good Ingredient?

This rates Fair: Acts as a humectant with preliminary support, so hydration gains are likely modest and formula-dependent. Risk: may trigger mild irritation in sensitive skin.