Acetyl Dipeptide-31 Amide

Acetyl Dipeptide-31 Amide is a water-soluble synthetic dipeptide modified with an amide group for stability. Serums and eye products use it for a firmer, smoother look and better feel, but the evidence so far is preliminary and mostly manufacturer-led.
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Ingredient Snapshot

Overview
A peptide used in eye products for a firmer, smoother look.
Category
Firming, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Aims to give a more lifted, refined look to skin texture. Evidence remains early and mostly manufacturer-generated, so results may vary.

Uses In Skincare & Cosmetics

Used in eye gels, neck treatments, and lightweight essences focused on a sleeker appearance. Can also be found in targeted firming serums.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Generally low irritation for a water‑soluble peptide, yet mild stinging is possible, especially near the eye area or on a compromised barrier. Introduce gradually if sensitive.

Is Acetyl Dipeptide-31 Amide a Good Ingredient?

Fair: firming/smoothing effects are based on preliminary, manufacturer-led evidence, so results may be modest. Irritation risk is usually low, but very sensitive skin could react.