Acetyl Dipeptide-31 Amide is a water-soluble synthetic dipeptide modified with an amide group for stability. Serums and eye products use it for a firmer, smoother look and better feel, but the evidence so far is preliminary and mostly manufacturer-led.
A peptide used in eye products for a firmer, smoother look.
Category
Firming, Tone/Texture
Type
Peptide
Ratings
Overall Rating
Fair
Comedogenic Risk
None
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Acetyl Dipeptide-31 Amide a Good Ingredient?
Fair: firming/smoothing effects are based on preliminary, manufacturer-led evidence, so results may be modest. Irritation risk is usually low, but very sensitive skin could react.
What it does
Skin Benefits
Aims to give a more lifted, refined look to skin texture. Evidence remains early and mostly manufacturer-generated, so results may vary.
Where you'll find it
Uses in Skincare & Cosmetics
Used in eye gels, neck treatments, and lightweight essences focused on a sleeker appearance. Can also be found in targeted firming serums.
Before you use it
Safety
Generally low irritation for a water‑soluble peptide, yet mild stinging is possible, especially near the eye area or on a compromised barrier. Introduce gradually if sensitive.