Acetyl Dipeptide-31 Amide

Acetyl Dipeptide-31 Amide is a water-soluble synthetic dipeptide modified with an amide group for stability. Serums and eye products use it for a firmer, smoother look and better feel, but the evidence so far is preliminary and mostly manufacturer-led.
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Snapshot

Overview
A peptide used in eye products for a firmer, smoother look.
Category
Firming, Tone/Texture
Type
Peptide

Ratings

Overall Rating

Fair

Comedogenic Risk

None

Not typically evaluated for comedogenicity — no standardized rating available.

Is Acetyl Dipeptide-31 Amide a Good Ingredient?

Fair: firming/smoothing effects are based on preliminary, manufacturer-led evidence, so results may be modest. Irritation risk is usually low, but very sensitive skin could react.

Skin Benefits

Aims to give a more lifted, refined look to skin texture. Evidence remains early and mostly manufacturer-generated, so results may vary.

Uses in Skincare & Cosmetics

Used in eye gels, neck treatments, and lightweight essences focused on a sleeker appearance. Can also be found in targeted firming serums.

Safety

Generally low irritation for a water‑soluble peptide, yet mild stinging is possible, especially near the eye area or on a compromised barrier. Introduce gradually if sensitive.