Acetyl Dipeptide-1 Cetyl Ester

Acetyl Dipeptide-1 Cetyl Ester is a lipidated dipeptide designed for improved skin affinity. Moisturizers and serums use it for a cushioned, smoother feel, though most of the supporting data comes from suppliers rather than independent studies.
Like this ingredient?

Ingredient Snapshot

Overview
A peptide that helps skin feel calmer, softer, and less tight.
Category
Soothing, Sensitive Skin, Skin Conditioning, Tone/Texture
Type
Peptide

Ingredient Ratings

Overall Rating

Fair

Comedogenic Risk

None

Skin Benefits

Helps skin feel calmer and softer, easing the sensation of tightness. Benefits are primarily supported by supplier-led data rather than strong clinical trials.

Uses In Skincare & Cosmetics

Included in creams, face oils, and night moisturizers for a cushioned afterfeel. Also appears in concentrated serums targeting comfort for reactive-feeling skin.

Comedogenic Rating

This ingredient is not typically evaluated for comedogenicity, and no standardized rating is available.

Safety

Typically well tolerated, with low irritation potential, though stinging can occur in reactive skin. No widely recognized regulatory restrictions; patch test if prone to sensitivity.

Is Acetyl Dipeptide-1 Cetyl Ester a Good Ingredient?

This rates Fair: comfort/soothing claims rely largely on supplier data with limited independent clinical support, so efficacy is uncertain. Generally low risk, but sensitive skin may experience mild irritation, particularly around the eyes.